Welcome to the Abell Group!
The function of peptides and proteins is defined by their linear sequence of amino acids and how this folds into a biologically active 3D shape or conformation. We are interested in using the tools of chemistry and biology to gain a detailed molecular understanding of these processes to allow the rational design and synthesize small molecules that can bind to a peptide or protein of interest. Such molecules provide important biological probes for studying key metabolic events and also potential therapies for important human diseases.
All our projects involve significant organic synthesis and product characterisation by NMR and other spectroscopic techniques, with an opportunity to get involved in some biology to broaden your experience. We work closely with many international academic and industrial collaborators and we have a strong interest in the commercialisation of basic research.
Professor Andrew D Abell